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Symptoms of Joint Pain: Aching, stiffness, swelling, reduced range of motion, and a feeling of instability

10.1080/10245332.2018.1456023 [DOI] [PubMed] [Google Scholar] Sharabi A., Cohen E., Sulkes J., Garty M

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Not because they're unsafe, but because the weight loss magnitude in controlled trials wasn't commercially viable compared to GLP-1 agonists or other obesity drugs