These overlapping effects not only inhibit tumour initiation and early progression but also render conventional therapies more efficacious sensitizing tumour cells to chemotherapy-mediated apoptosis, protecting normal tissues against radiation-induced oxidative damage, dampening chemotherapy-associated inflammation (e.g
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Leveraging human genetic data to investigate the cardiometabolic effects of glucose-dependent insulinotropic polypeptide signalling
Biochem Biophys Res Commun 400(4):511516
Oral formulations have been investigated for their potential effects on the stomach, intestines, and gastrointestinal lining while also being evaluated for broader systemic activity