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Future Med Chem 6(15):167798

Protein S-glutathionylation stimulate adipogenesis by stabilizing C/EBPbeta in 3T3L1 cells

While this packaging protects the DNA from some forms of damage, it also limits the sperm cells ability to repair oxidative damage, such as DNA fragmentation caused by ROS

Hilleringmann M, Pansegrau W, Doyle M, Kaufman S, MacKichan ML, Gianfaldoni C, Ruggiero P, Covacci A (2006) Inhibitors of Helicobacter pylori ATPase Cag block CagA transport and cag virulence

Preclinical Toxicology: Toxicity studies in rodents indicate that even high doses (e.g., 20 mg/kg) do not result in gross organ toxicity or lethality in the acute setting

Inhibition of the copper transporter SLC31A1 in pancreatic cancer cells results in decreased intracellular copper concentrations and enhances autophagy (Yu et al., 2019)