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For special situations like vacations or event-filled weekends, receiving treatment multiple times in a week is generally safe for most healthy individuals

BMJ 2021:372

For example, one study found that taking 1,0002,000 micrograms orally in properly timed doses helped improve levels as much as injections

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This neurobiological shift would represent a functional change in food reward rather than a peripheral taste bud alteration, though human evidence remains limited