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Similar conformational changes between two particle states are seen in other GSH-binding enteroviruses, and thus the use of GSH affinity columns for enterovirus purification will likely select for the D-antigenic states and could lead to loss/removal of material for less stable viruses and VLPs 37

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Phospholipid-hydroperoxide glutathione peroxidase (GPx-4) localization in resting platelets, and compartmental change during platelet activation