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To absorb vitamin B12 effectively, your body requires an intact stomach and gut, a well-functioning pancreas, and sufficiently high levels of intrinsic factor, a protein that binds to vitamin B12 in the stomach (1)

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Adding 2ml creates 1mg/ml (1000mcg/ml)

The people who are at the highest risk of B12 insufficiency or deficiency are older adults, those with atrophic gastritis, gastrointestinal disorders, pernicious anemia, those who have had gastrointestinal surgery, vegans, and vegetarians

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If you have been feeling run down, the useful first move is to find out whether B12 is actually the issue