The lead author of the 2025 narrative review titled "Regeneration or Risk?" emphasized the urgent need for randomized controlled trials
And quite often, it points to the same thing: low vitamin B12
The fundamental difference is whether GHK-Cu is included
Reasonable markers to track: waist circumference, weight, resting heart rate, sleep quality, and a basic liver panel (ALT, AST) before and after long cycles
Medications know to cause bone marrow suppression (e.g., myelosuppressive antineoplastic agents) may result in a blunted or impeded response to methylcobalamin, vitamin B12 therapy
One of the most significant areas of many peoples self-image that prevents happiness is having extra weight to carry around