doi: 10.1186/s12890-022-02262-x 25 CherianSVKumarAAkasapuKAshtonRWAparnathMMalhotraA
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Under hypoxic conditions, lactate could enter fibrogenic mesenchymal progenitor cells through the GPR81 receptor to enhance their self-renewal, intensified by HIF-1 augmenting GPR81 expression [180]