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Sustained receptor engagement allows continuous activation of satiety pathways without repeated peaks and troughs

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Neuroactive peptides work through mechanisms such as brain-derived neurotrophic factor (BDNF) upregulation, HGF/c-Met signaling, and modulation of monoamine neurotransmitters (Table 4)

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Cancer history or active malignancy: The peptide angiogenic properties could theoretically promote tumor vascularization

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