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PI3K/Akt/mTOR Signaling Cascade A primary downstream pathway of IGF-1R activation is the PI3K/Akt/mTOR cascade, which regulates cell survival, protein synthesis, and metabolic homeostasis

Ferroptosis, a unique form of programmed cell death characterized by irondependent lipid peroxidation, has been increasingly recognized for its essential role in the progression of various neurodegenerative diseases and diabetesassociated cognitive impairment

Being overweight or worse being obese is a serious problem not just in the US but also in other parts of the world

The long-term use of synthetic drugs can undeniably causes many side effects in patients

Bile aids in the removal of toxic substances and serves as a filter that separates out harmful substances from the bloodstream and excretes them [4]

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