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Minor inconsistencies in size, surface charge, or encapsulation efficiency can impact their therapeutic efficacy

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Farhadi M, Salem MM, Asghari A, Daneshi A, Mirsalehi M, Mahmoudian S

However, many patients can begin injections right away if theyre showing symptoms of deficiency, as B12 is very safe

Upon ligand binding, the nanoparticle-receptor complex is internalized via clathrin-coated vesicles to be transported across the BBB and subsequently released by exocytosis into the brain parenchyma 119,120