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The samples had been previously used and published by Quan Tang et al

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Some of these compounds subsequently advanced to clinical trials for schizophrenia (Yang and Svensson 2008

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Additionally, it was reported that trimetazidine (TMZ), a piperazine derivative, mediated activation of the GSH system and had antioxidant and cytoprotective effects in several myocardial injury models [210,211,212,213]