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They appear in coffee, cereals, beans, grape juice, wine, spices, dry vine fruits, and licorice

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[80] While specific clinical evidence remains limited, theoretical concerns exist regarding melatonins potential to counteract immunosuppressive effects in organ transplant recipients or patients with autoimmune conditions

10.1002/hep.28251 110 TangD.ChenX.KangR.KroemerG

10.3389/fendo.2022.992666 149 PowersS

(Source 2) "Interventions that increase NAD+, including supplementing with NAD+ directly, may slow the aging process." Reason #2 - Reduce Disease Risk Higher NAD+ levels from liposomal supplementation increase sirtuins