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Consistent with these functional data, transcriptional analysis revealed reduced expression of genes encoding core mitochondrial components of the oxidative phosphorylation machinery

It was suggested that imbalanced gut microbiota and aberrant metabolites contribute to the progression of obesity, which is linked to the modulation of energy homeostasis, fat accumulation, and decreased lipoprotein lipase activity (148)

In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation

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