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The initial stage in NTBI absorption involves the reduction of Fe 3+ to Fe 2+ facilitated by a membrane-associated ferrireductase [16]

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It does not constitute guidance on human or animal use and should not be interpreted as such

The NLRP3 inflammasome inhibitor OLT1177 rescues cognitive impairment in a mouse model of Alzheimers disease

The CMH test will also be used to assess treatment differences for the secondary efficacy endpoints