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Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6

This therapy makes sense for people who want cleaner energy turnover: the founder cycling through long workdays and late-night workouts, the patient on GLP-1s who feels sluggish as calories shift, or the lifter trying to maintain performance while cutting

Lu, Y.-S., Wong, A

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The elevated B12 appears to be a consequence of disease activity, likely resulting from increased production of B12-binding proteins by tumor cells or from liver involvement in the cancer process