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Chronic alcohol consumption increases the generation of reactive oxygen species (ROS) in hepatocytes, primarily through alcohol metabolism via alcohol dehydrogenase, cytochrome P450 2E1, and mitochondrial respiratory chain dysfunction [12, 42]
5) Some medications like fluoxetine (an inhibitor of 5-HT capture) have both anti-inflammatory and anti-depressant effects (205, 300)
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Shao et al
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