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We found that PPARa over-expression significantly up-regulated FSP1 expression in neuron after TSCI, thus promoted the expression of CoQ10 and content of NADH, while icFSP1 inhibited this phenomenon, suggesting that FSP1 is a key effector of PPARa mediated lipid peroxidation related neuronal ferroptosis protection

10.1016/j.bbagen.2012.10.006 34 FangZ.RobertsA

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All 3 forms of SOD (CuZn-SOD, Mn-SOD, and EC-SOD) are widely expressed in the human lung [46, 47]