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Sharon G, Cruz NJ, Kang D-W, Gandal MJ, Wang B, Kim Y-M, et al

PMID: 20933444

The potential benefits of MIC B12 injections extend beyond weight loss

To investigate the effect of gene knockout on l-cysteine and GSH degradation, the engineered strains were cultured in the flasks as described above and the cells were collected by centrifugation (6000 rpm, 4 C for 5 min) after two washes with 50 mM phosphate buffer (pH7.0)

As anticipated, the data in Figure 25 demonstrate that both D-Nle-Cys-Ile-NH-(CH 2 ) 5 -CONH 2 and D-Nle-Tyr-He-NH-(CH 2 )s-CONH 2 , which bind HGF with high affinity (Figure 23) and effectively block its dimerization (Figure 24) were able to block Met auto-phosphorylation